Ofloxacin: Uses, Dosage, Side Effects, and Practical Tips
Ofloxacin is a fluoroquinolone antibiotic used to treat a range of bacterial infections. It works by stopping bacteria from reproducing so the immune system can clear the infection. Doctors prescribe it for urinary tract infections, some respiratory infections, skin infections, and certain sexually transmitted infections. It is not effective against viruses like the common cold or flu.
How to take ofloxacin
Take ofloxacin exactly as your doctor tells you. Common adult doses are 200–400 mg once or twice daily depending on the infection and kidney function; never change dose without medical advice. Take tablets with a full glass of water. Avoid calcium, magnesium, iron, zinc supplements and antacids within two hours because they reduce absorption. Finish the entire course even if you feel better to avoid resistance.
Side effects and precautions
Most people have mild side effects like nausea, diarrhea, headache, or dizziness. Serious reactions can include tendon pain or rupture, nerve damage (peripheral neuropathy), mood changes, or irregular heart rhythm. Risks increase with corticosteroid use, older age, and kidney problems. If you notice persistent tendon pain, numbness, severe dizziness, or fainting, stop the drug and seek medical help. Pregnant people, breastfeeding mothers, and children generally should avoid fluoroquinolones unless no safer option exists.
Drug interactions and safety tips
Ofloxacin interacts with blood thinners like warfarin, some diabetes drugs, and psychiatric medicines that affect heart rhythm. Always tell your doctor about all prescriptions, supplements, and herbal products you take. Avoid driving or heavy machinery if you feel dizzy or have blurred vision. Protect your skin from strong sunlight while taking ofloxacin; wear sunscreen and avoid tanning because of photosensitivity.
When to use antibiotics and resistance
Only use ofloxacin for confirmed or strongly suspected bacterial infections. Overusing powerful antibiotics fuels resistant bacteria that are harder to treat. If possible, ask for culture and sensitivity testing so treatment targets the actual bug. If symptoms fail to improve in 48–72 hours, call your healthcare provider rather than extending treatment alone.
Buying and storage
Buy ofloxacin only from licensed pharmacies with a valid prescription. Check packaging for tampering and use the manufacturer and batch number if you doubt authenticity. Store tablets at room temperature away from moisture and heat, and keep them out of reach of children.
Monitoring and follow-up
People on prolonged or high-dose ofloxacin should have kidney function and liver tests checked if advised by their doctor. Blood tests may be needed if you have kidney disease or take other medicines that affect kidneys. Keep a list of side effects and report new symptoms promptly so your prescriber can adjust treatment.
When to seek care
Call emergency services or go to urgent care if you have severe tendon pain, breathing trouble, severe allergic reaction, fainting, or signs of liver trouble like yellowing skin or dark urine. Immediately.
Want more reading?
If you want practical reads on antibiotics and safe medicine buying, check our guides on tetracycline, secnidazole, and tips for finding reputable online pharmacies.